| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C7 (22-270) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
C7 |
| Gene ID: |
730 |
| Uniprot ID: |
CO7_HUMAN |
| Immunogen Region: |
22-270 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 22-270 of human C7 (NP_000578.2). |
| Immunogen Sequence: |
ASSPVNCQWDFYAPWSECNG CTKTQTRRRSVAVYGQYGGQ PCVGNAFETQSCEPTRGCPT EEGCGERFRCFSGQCISKSL VCNGDSDCDEDSADEDRCED SERRPSCDIDKPPPNIELTG NGYNELTGQFRNRVINTKSF GGQCRKVFSGDGKDFYRLSG NVLSYTFQVKINNDFNYEFY NSTWSYVKHTSTEHTSSSRK RSFFRSSSSSSRSYTSHTNE IHKGKSYQLLVVENTVEVA |
| Post Translational Modifications | C7 has 28 disulfide bridges. C-, N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. |
| Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. |
| Protein Name | Complement Component C7 |
| Database Links | Reactome: R-HSA-166665Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Complement Component C7 antibodyAnti-C7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
