| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-C5a anaphylatoxin chemotactic receptor 2 (270-350 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | C5AR2 |
| Gene ID: | 27202 |
| Uniprot ID: | C5AR2_HUMAN |
| Immunogen Region: | 270-350 aa |
| Specificity: | C5ARL Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 270-350 |
| Function | Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways. |
| Protein Name | C5a Anaphylatoxin Chemotactic Receptor 2Complement Component 5a Receptor 2G-Protein Coupled Receptor 77 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-977606 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C5a Anaphylatoxin Chemotactic Receptor 2 antibodyAnti-Complement Component 5a Receptor 2 antibodyAnti-G-Protein Coupled Receptor 77 antibodyAnti-C5AR2 antibodyAnti-C5L2 antibodyAnti-GPR77 antibody |
Information sourced from Uniprot.org