Host: |
Rabbit |
Applications: |
IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-C3a anaphylatoxin chemotactic receptor (175-224 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
C3AR1 |
Gene ID: |
719 |
Uniprot ID: |
C3AR_HUMAN |
Immunogen Region: |
175-224 aa |
Specificity: |
C3aR Polyclonal Antibody detects endogenous levels of C3aR protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human C3AR1 at the amino acid range 175-224 |
Post Translational Modifications | Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin. O-glycosylated. |
Function | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. |
Protein Name | C3a Anaphylatoxin Chemotactic ReceptorC3arC3a-R |
Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594Reactome: R-HSA-6798695Reactome: R-HSA-9660826Reactome: R-HSA-977606 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-C3a Anaphylatoxin Chemotactic Receptor antibodyAnti-C3ar antibodyAnti-C3a-R antibodyAnti-C3AR1 antibodyAnti-AZ3B antibodyAnti-C3R1 antibodyAnti-HNFAG09 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance