| Short Description : | Rabbit polyclonal anti-C3a anaphylatoxin chemotactic receptor (175-224 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | C3AR1 |
| Gene ID: | 719 |
| Uniprot ID: | C3AR_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human C3AR1 at the amino acid range 175-224 |
| Immunogen Region: | 175-224 aa |
| Specificity: | C3aR Polyclonal Antibody detects endogenous levels of C3aR protein. |
| Post Translational Modifications | Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin. O-glycosylated. |
| Function | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. |
| Protein Name | C3a Anaphylatoxin Chemotactic ReceptorC3arC3a-R |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594Reactome: R-HSA-6798695Reactome: R-HSA-9660826Reactome: R-HSA-977606 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C3a Anaphylatoxin Chemotactic Receptor antibodyAnti-C3ar antibodyAnti-C3a-R antibodyAnti-C3AR1 antibodyAnti-AZ3B antibodyAnti-C3R1 antibodyAnti-HNFAG09 antibody |
Information sourced from Uniprot.org
