Anti-C2GnT-M antibody (273-284) (STJ71416)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-C2GnT-M (273-284) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:2000.WB: Approx. 50kDa band observed in Human Lymph Node lysates (calculated MW of 50.9kDa according to NP_004742.1). In transfected HEK293 transiently expressing GCNT3 a band of approx. 55kDa i |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | GCNT3 |
| Gene ID | 9245 |
| Uniprot ID | GCNT3_HUMAN |
| Accession Number | NP_004742.1 |
| Immunogen Region | 273-284 |
| Immunogen Sequence | RDTLHLTNKKKD |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. |
| Protein Name | Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3 C2gnt-Mucin TypeC2gnt-MHc2gnt-MCore 2/Core 4 Beta-1 -6-N-AcetylglucosaminyltransferaseC2/4gnt |
| Database Links | Reactome: R-HSA-913709 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3 antibodyAnti-C2gnt-Mucin Type antibodyAnti-C2gnt-M antibodyAnti-Hc2gnt-M antibodyAnti-Core 2/Core 4 Beta-1 -6-N-Acetylglucosaminyltransferase antibodyAnti-C2/4gnt antibodyAnti-GCNT3 antibody |
Information sourced from Uniprot.org