• Immunofluorescence analysis of NIH/3T3 cells using C1R Rabbit polyclonal antibody (STJ11105539) at a dilution of 1:150 (40x lens). Secondary antibody:Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunohistochemistry analysis of C1R in paraffin-embedded human liver cancer tissue using C1R Rabbit polyclonal antibody (STJ11105539) at a dilution of 1:100 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Immunohistochemistry analysis of C1R in paraffin-embedded rat spleen tissue using C1R Rabbit polyclonal antibody (STJ11105539) at a dilution of 1:100 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.

Anti-C1R antibody (18-190) (STJ11105539)

SKU:
STJ11105539

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Complement C1r Subcomponent (18-190) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: C1R
Gene ID: 715
Uniprot ID: C1R_HUMAN
Immunogen Region: 18-190
Immunogen: Recombinant Protein corresponding to a sequence within amino acids 18-190 of human C1R (NP_001724.4).
Immunogen Sequence: SIPIPQKLFGEVTSPLFPKP YPNNFETTTVITVPTGYRVK LVFQQFDLEPSEGCFYDYVK ISADKKSLGRFCGQLGSPLG NPPGKKEFMSQGNKMLLTFH TDFSNEENGTIMFYKGFLAY YQAVDLDECASRSKSGEEDP QPQCQHLCHNYVGGYFCSCR PGYELQEDTHSCQ
Post Translational Modifications The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
Function C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
Protein Name Complement C1r Subcomponent
Complement Component 1 Subcomponent R Cleaved Into - Complement C1r Subcomponent Heavy Chain - Complement C1r Subcomponent Light Chain
Database Links Reactome: R-HSA-166663
Reactome: R-HSA-173623
Reactome: R-HSA-977606
Cellular Localisation Secreted
Alternative Antibody Names Anti-Complement C1r Subcomponent antibody
Anti-Complement Component 1 Subcomponent R Cleaved Into - Complement C1r Subcomponent Heavy Chain - Complement C1r Subcomponent Light Chain antibody
Anti-C1R antibody

Information sourced from Uniprot.org

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