| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | C1QC |
| Gene ID: | 714 |
| Uniprot ID: | C1QC_HUMAN |
| Immunogen Region: | 50-150 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human C1QC (NP_001107573.1). |
| Immunogen Sequence: | YDGLPGPKGEPGIPAIPGIR GPKGQKGEPGLPGHPGKNGP MGPPGMPGVPGPMGIPGEPG EEGRYKQKFQSVFTVTRQTH QPPAPNSLIRFNAVLTNPQG D |
| Post Translational Modifications | O-linked glycans consist of Glc-Gal disaccharides bound to the oxygen atom of post-translationally added hydroxyl groups. |
| Function | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
| Protein Name | Complement C1q Subcomponent Subunit C |
| Database Links | Reactome: R-HSA-166663Reactome: R-HSA-173623Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Complement C1q Subcomponent Subunit C antibodyAnti-C1QC antibodyAnti-C1QG antibody |
Information sourced from Uniprot.org