Host: |
Rabbit |
Applications: |
ELISA/IHC/IP/WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-C1orf146 (100-180) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Purification: |
Affinity Purified |
Concentration: |
0.68-0.70 µg/µl |
Dilution Range: |
WB: 1:500DB: 1:4, 000ELISA: 1:4, 000IP: 1:150IHC: 1:50-1:100 |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
SPO16 |
Gene ID: |
388649 |
Uniprot ID: |
SPO16_HUMAN |
Immunogen Region: |
100-180 |
Immunogen: |
Synthetic peptide taken within amino acid region 100-180 on human C1orf146 protein. |
Function | Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells. Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1. Required for the localization of TEX11 and MSH4 to recombination intermediates. |
Protein Name | Protein Spo16 HomologSynaptonemal Complex Reinforcing Element |
Cellular Localisation | Chromosome |
Alternative Antibody Names | Anti-Protein Spo16 Homolog antibodyAnti-Synaptonemal Complex Reinforcing Element antibodyAnti-SPO16 antibodyAnti-C1orf146 antibodyAnti-SCRE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance