| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-C1D (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.1-0.3µg/mlELISA-antibody detection limit dilution 1:128000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
C1D |
| Gene ID: |
10438 |
| Uniprot ID: |
C1D_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_775269.1 |
| Specificity: |
Reported variants represent identical protein: NP_006324.1, NP_775269.1. |
| Immunogen Sequence: |
SKNASKVANKGKSKS |
| Post Translational Modifications | Phosphorylated by PRKDC. |
| Function | Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB. |
| Protein Name | Nuclear Nucleic Acid-Binding Protein C1dHc1d |
| Database Links | Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusCytoplasmNucleolusExosc10 Is Required For Nucleolar LocalizationColocalizes With Tsnax In The Nucleus |
| Alternative Antibody Names | Anti-Nuclear Nucleic Acid-Binding Protein C1d antibodyAnti-Hc1d antibodyAnti-C1D antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
