| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RMC1 |
| Gene ID: | 29919 |
| Uniprot ID: | RMC1_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human C18orf8 (NP_037458.3). |
| Immunogen Sequence: | MGEEDYYLELCERPVQFEKA NPVNCVFFDEANKQVFAVRS GGATGVVVKGPDDRNPISFR MDDKGEVKCIKFSLENKILA VQRTSKTVDFCNFIPDNSQL EYTQECKTKNANILGFCWTS STEIVFITDQGIEFYQVLPE KRSLKLLKSHNLNVNWYMYC PESAVILLSTTVLENVLQPF HFRAGTMSKLPKFEIELPAA PKSTKPSLSERDIAMATIYG QLYVLFLRHHSRTSNSTGA |
| Function | Componement of the CCZ1-MON1 RAB7A guanine exchange factor (GEF). Acts as a positive regulator of CCZ1-MON1A/B function necessary for endosomal/autophagic flux and efficient RAB7A localization. |
| Protein Name | Regulator Of Mon1-Ccz1 ComplexColon Cancer-Associated Protein Mic1Mic-1Wd Repeat-Containing Protein 98 |
| Cellular Localisation | Lysosome MembraneLate Endosome Membrane |
| Alternative Antibody Names | Anti-Regulator Of Mon1-Ccz1 Complex antibodyAnti-Colon Cancer-Associated Protein Mic1 antibodyAnti-Mic-1 antibodyAnti-Wd Repeat-Containing Protein 98 antibodyAnti-RMC1 antibodyAnti-C18orf8 antibodyAnti-MIC1 antibodyAnti-WDR98 antibody |
Information sourced from Uniprot.org