Anti-c-kit Oncoprotein antibody [T595] (STJ16101694)

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STJ16101694-1
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Short Description :Mouse monoclonal anti-c-kit Oncoprotein for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :T595
Isotype:IgG1k
Conjugation:Unconjugated
Concentration:>=30 mg/L
Dilution Range:IHC-P 1:40
Formulation:Tissue culture supernatant with sodium azide
Storage Instruction:Store at 2-8°C for up to 1-year, upon receipt.
Immunogen:Prokaryotic recombinant protein corresponding to the three N-terminal C2-like extracellular domains of the human c-kit oncoprotein molecule.
Background The c-kit proto-oncogene encodes a transmembrane receptor with tyrosine kinase activity, c-kit (CD117) , which is closely-related to the platelet-derived growth factor receptor family. c-kit plays a role during hematopoiesis, gametogenesis and melanogenesis. The expression of CD117 antigen is of particular interest in the study of gastrointestinal stromal tumors (GIST) , small lung cell carcinomas and in melanomas.

Information sourced from Uniprot.org