| Host: | Mouse | 
| Applications: | IHC-P | 
| Reactivity: | Human | 
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. | 
| Short Description : | Mouse monoclonal antibody anti-c-kit Oncoprotein is suitable for use in Immunohistochemistry research applications. | 
| Clonality : | Monoclonal | 
| Clone ID : | T595 | 
| Conjugation: | Unconjugated | 
| Isotype: | IgG1k | 
| Formulation: | Tissue culture supernatant with sodium azide | 
| Concentration: | >=30 mg/L | 
| Dilution Range: | IHC-P 1:40 | 
| Storage Instruction: | Store at 2-8°C upon receipt. | 
| Immunogen: | Prokaryotic recombinant protein corresponding to the three N-terminal C2-like extracellular domains of the human c-kit oncoprotein molecule. | 
| Background | The c-kit proto-oncogene encodes a transmembrane receptor with tyrosine kinase activity, c-kit (CD117) , which is closely-related to the platelet-derived growth factor receptor family. c-kit plays a role during hematopoiesis, gametogenesis and melanogenesis. The expression of CD117 antigen is of particular interest in the study of gastrointestinal stromal tumors (GIST) , small lung cell carcinomas and in melanomas. | 
Information sourced from Uniprot.org
 
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