| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-BTB/POZ domain-containing protein 8 (224-274 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BTBD8 |
| Gene ID: | 284697 |
| Uniprot ID: | BTBD8_HUMAN |
| Immunogen Region: | 224-274 aa |
| Specificity: | This antibody detects endogenous levels of human BTBD8 |
| Immunogen: | Synthesized peptide derived from the human BTBD8 at the amino acid range 224-274 |
| Function | Involved in clathrin-mediated endocytosis at the synapse. Plays a role in neuronal development and in synaptic vesicle recycling in mature neurons, a process required for normal synaptic transmission. |
| Protein Name | Btb/Poz Domain-Containing Protein 8Ap2-Interacting Clathrin-EndocytosisApache |
| Cellular Localisation | Cell ProjectionAxonPresynapseCytoplasmic VesicleClathrin-Coated VesicleNucleusIn Primary CulturesMainly Present At Axonal And Presynaptic Terminal Levels Of Mature NeuronsIn Immature NeuronsLocalizes To The Cell Body And Growing ProcessesIncluding AxonsLocalized To Nucleus In Fetal Cells |
| Alternative Antibody Names | Anti-Btb/Poz Domain-Containing Protein 8 antibodyAnti-Ap2-Interacting Clathrin-Endocytosis antibodyAnti-Apache antibodyAnti-BTBD8 antibodyAnti-KIAA1107 antibody |
Information sourced from Uniprot.org