Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Transcription factor IIIB 50 kDa subunit is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
BRF2 |
Gene ID: |
55290 |
Uniprot ID: |
BRF2_HUMAN |
Specificity: |
This antibody detects endogenous levels of BRF2 at Human, Mouse, Rat |
Immunogen: |
Synthesized peptide derived from human BRF2 |
Function | General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression.functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress. |
Protein Name | Transcription Factor Iiib 50 Kda SubunitTfiiib50Htfiiib50B-Related Factor 2Brf-2Hbrfu |
Database Links | Reactome: R-HSA-749476Reactome: R-HSA-76071 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Transcription Factor Iiib 50 Kda Subunit antibodyAnti-Tfiiib50 antibodyAnti-Htfiiib50 antibodyAnti-B-Related Factor 2 antibodyAnti-Brf-2 antibodyAnti-Hbrfu antibodyAnti-BRF2 antibodyAnti-BRFU antibodyAnti-PRO1470 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance