| Function | Exhibits 3'-nucleotidase activity toward adenosine 3',5'-bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, I(1,3,4)P3, I(1,4,5)P3 and I(1,3,4,5)P4. |
| Protein Name | Golgi-Resident Adenosine 3' -5'-Bisphosphate 3'-PhosphataseGolgi-Resident Pap PhosphataseGpapp3'(2' - 5'-Bisphosphate Nucleotidase 2Inositol Monophosphatase Domain-Containing Protein 1Myo-Inositol Monophosphatase A3Phosphoadenosine Phosphate 3'-Nucleotidase |
| Database Links | Reactome: R-HSA-156584 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembraneSingle-Pass Type Ii Membrane ProteinThe Catalytic Core Is Predicted To Reside Within The Golgi Lumen |
| Alternative Antibody Names | Anti-Golgi-Resident Adenosine 3' -5'-Bisphosphate 3'-Phosphatase antibodyAnti-Golgi-Resident Pap Phosphatase antibodyAnti-Gpapp antibodyAnti-3'(2' - 5'-Bisphosphate Nucleotidase 2 antibodyAnti-Inositol Monophosphatase Domain-Containing Protein 1 antibodyAnti-Myo-Inositol Monophosphatase A3 antibodyAnti-Phosphoadenosine Phosphate 3'-Nucleotidase antibodyAnti-BPNT2 antibodyAnti-IMPA3 antibodyAnti-IMPAD1 antibody |
Information sourced from Uniprot.org
