• Anti-BMPR2 antibody [3F6] (STJ97877)
  • Immunohistochemistry analysis of paraffin-embedded muscle tissues (left) and kidney cancer tissues (right) with DAB staining using BMPR-II monoclonal antibody.
  • Immunofluorescence analysis of Eca109 cells using BMPR-II monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • Western blot analysis using BMPR-II monoclonal antibody against HeLa (1) , A431 (2) , NIH/3T3 (3) , Cos7 (4) and PC-12 (5) cell lysate.

Anti-BMPR2 antibody [3F6] (STJ97877)

SKU:
STJ97877

£139.00 - £336.00
Current Stock:
Host: Mouse
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat/Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Bone morphogenetic protein receptor type-2 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Monoclonal
Clone ID: 3F6
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC 1:200-1:1000
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BMPR2
Gene ID: 659
Uniprot ID: BMPR2_HUMAN
Specificity: BMPR-II Monoclonal Antibody detects endogenous levels of BMPR-II protein.
Immunogen: Purified recombinant fragment of human BMPR-II expressed in E. Coli.
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
Protein Name Bone Morphogenetic Protein Receptor Type-2
Bmp Type-2 Receptor
Bmpr-2
Bone Morphogenetic Protein Receptor Type Ii
Bmp Type Ii Receptor
Bmpr-Ii
Database Links Reactome: R-HSA-201451
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Bone Morphogenetic Protein Receptor Type-2 antibody
Anti-Bmp Type-2 Receptor antibody
Anti-Bmpr-2 antibody
Anti-Bone Morphogenetic Protein Receptor Type Ii antibody
Anti-Bmp Type Ii Receptor antibody
Anti-Bmpr-Ii antibody
Anti-BMPR2 antibody
Anti-PPH1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance