• Immunofluorescence analysis of Mouse kidney tissue using BMPR1B Rabbit polyclonal antibody (STJ119430) at a dilution of 1:600 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining. High pressure antigen retrieval performed with 0. 01M Citrate Buffer (pH 6. 0) prior to IF staining.
  • Immunohistochemistry analysis of BMPR1B in paraffin-embedded rat ovary using BMPR1B Rabbit polyclonal antibody (STJ119430) at dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of BMPR1B in paraffin-embedded human colon carcinoma using BMPR1B Rabbit polyclonal antibody (STJ119430) at dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of BMPR1B in paraffin-embedded human mammary cancer using BMPR1B Rabbit polyclonal antibody (STJ119430) at dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.

Anti-BMPR1B antibody (1-126) (STJ119430)

SKU:
STJ119430

£112.50 - £522.50
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Host: Rabbit
Applications: IHC
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BMPR1B (1-126) is suitable for use in Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BMPR1B
Gene ID: 658
Uniprot ID: BMR1B_HUMAN
Immunogen Region: 1-126
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-126 of human BMPR1B (NP_001194.1).
Immunogen Sequence: MLLRSAGKLNVGTKKEDGES TAPTPRPKVLRCKCHHHCPE DSVNNICSTDGYCFTMIEED DSGLPVVTSGCLGLEGSDFQ CRDTPIPHQRRSIECCTERN ECNKDLHPTLPPLKNRDFVD GPIHHR
Post Translational Modifications Autophosphorylated.
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.
Protein Name Bone Morphogenetic Protein Receptor Type-1b
Bmp Type-1b Receptor
Bmpr-1b
Cd Antigen Cdw293
Database Links Reactome: R-HSA-201451
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Bone Morphogenetic Protein Receptor Type-1b antibody
Anti-Bmp Type-1b Receptor antibody
Anti-Bmpr-1b antibody
Anti-Cd Antigen Cdw293 antibody
Anti-BMPR1B antibody

Information sourced from Uniprot.org

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