| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BLZF1 |
| Gene ID: | 8548 |
| Uniprot ID: | GO45_HUMAN |
| Immunogen Region: | 1-400 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-400 of human BLZF1 (NP_003657.1). |
| Immunogen Sequence: | MTTKNLETKVTVTSSPIRGA GDGMETEEPPKSVEVTSGVQ SRKHHSLQSPWKKAVPSESP GVLQLGKMLTEKAMEVKAVR ILVPKAAITHDIPNKNTKVK SLGHHKGEFLGQSEGVIEPN KELSEVKNVLEKLKNSERRL LQDKEGLSNQLRVQTEVNRE LKKLLVASVGDDLQYHFERL AREKNQLILENEALGRNTAQ LSEQLERMSIQCDVWRSKFL ASRVMADELTNSRAALQRQ |
| Tissue Specificity | Detected in adrenal gland. |
| Post Translational Modifications | ADP-ribosylated by tankyrase TNKS and TNKS2. Poly-ADP-ribosylated protein is recognized by RNF146, followed by ubiquitination. Ubiquitinated by RNF146 when poly-ADP-ribosylated, leading to its degradation. |
| Function | Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface. |
| Protein Name | Golgin-45Basic Leucine Zipper Nuclear Factor 1Jem-1P45 Basic Leucine-Zipper Nuclear Factor |
| Database Links | Reactome: R-HSA-162658 |
| Cellular Localisation | Golgi Apparatus MembraneIsoform 1: NucleusDetected In The Nucleus Upon Heterologous ExpressionNot Detected In The CytoplasmIsoform 2: CytoplasmNot Detected In The Nucleus |
| Alternative Antibody Names | Anti-Golgin-45 antibodyAnti-Basic Leucine Zipper Nuclear Factor 1 antibodyAnti-Jem-1 antibodyAnti-P45 Basic Leucine-Zipper Nuclear Factor antibodyAnti-BLZF1 antibodyAnti-JEM1 antibody |
Information sourced from Uniprot.org
