Anti-Blood Group A (CD173) antibody [HE-10] (STJ16100160)

SKU:
STJ16100160

£264.50 - £1,448.50
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Host: Mouse
Applications: AGG/FC/IF/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Blood Group A (CD173) is suitable for use in AGG, Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: HE-10
Conjugation: Unconjugated
Isotype: IgMk
Formulation: PBS with 0.02% Sodium Azide.
Purification: Affinity purified from tissue culture.
Concentration: Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Dilution Range: Agglutination. Flow cytometry (0, 5–1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (0, 5–1 µg/ml). Immunohistology (formalin-fixed: 1-2 µg/ml for 30 min. at RT; requires boiling tissue sections in 10mM citrate buffer, pH 6, 0, for 10-20 min fo
Storage Instruction: Store for up to 1 year at 2-8°C upon receipt.
Immunogen: A BALB/c mouse was immunized with a mixture of erythrocytes of blood group A1 and a glycoprotein fraction isolated from the saliva of secretors with blood group A of human origin. Fusion partner: P3-X63-Ag8.653.
Background Agglutinates erythrocytes of group A, and is excellent as a tumour marker in patients ofblood group B and 0. It does not agglutinate erythrocytes of group B and 0. Study with specificoligosaccharides showed that the antibody HE-10 reacts with A and H antigens with chain types 3 and4 and it does not react with A disaccharide, A trisaccharide, A type 1, A type 2, ALeb. The antibody HE-10 does not react with normal tissue sections of donors with blood group B and 0 but it reactsspecifically with malignant tissues.Immunogen: Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva ofsecretors with blood group A.

Information sourced from Uniprot.org

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