Anti-Blood Group A-CD173 antibody [3-3A] (STJ16100981)

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STJ16100981
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Short Description :Mouse monoclonal antibody anti-Blood Group A-CD173 is suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications.
Applications:FC/IF/IHC
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :3-3A
Isotype:IgG1k
Conjugation:Unconjugated
Concentration:Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Purification:Affinity purified from tissue culture.
Dilution Range:Flow Cytometry (0, 5 – 1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (0, 5 – 1, 0 µg/ml). Immunohistology (formalin-fixed: 1-2 µg/ml for30 min at RT; requires boiling tissue sections in 10mM Citrate Buffer, pH 6, 0, for 10-20 min followed by
Formulation:PBS with 0.02% Sodium Azide.
Storage Instruction:Store for up to 1 year at 2-8°C upon receipt.
Immunogen:A BALB/c mouse was immunized with mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classification). Fusion partner: SP2/0.
Background 3-3A reacts with determinants of chain A type 3 and 4 and chain H type 3 and 4, but not with type 1 and 2 chain structures. It is not reactive with immunodominant A trisaccharide. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas. 3-3A does not react with normal tissue sections of donors with blood group B and 0 but it reacts specifically with malignant tissues in these individuals.

Information sourced from Uniprot.org