Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Bcl-2-interacting killer (18-67) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
BIK |
Gene ID: |
638 |
Uniprot ID: |
BIK_HUMAN |
Immunogen Region: |
18-67 |
Specificity: |
NBK Polyclonal Antibody detects endogenous levels of NBK protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human BIK. AA range:18-67 |
Post Translational Modifications | Proteolytically cleaved by RHBDL4/RHBDD1. RHBDL4/RHBDD1-induced cleavage is a necessary step prior its degradation by the proteosome-dependent mechanism. |
Function | Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX. |
Protein Name | Bcl-2-Interacting KillerApoptosis Inducer NbkBip1Bp4 |
Cellular Localisation | Endomembrane SystemSingle-Pass Membrane ProteinMitochondrion MembraneAround The Nuclear EnvelopeAnd In Cytoplasmic Membranes |
Alternative Antibody Names | Anti-Bcl-2-Interacting Killer antibodyAnti-Apoptosis Inducer Nbk antibodyAnti-Bip1 antibodyAnti-Bp4 antibodyAnti-BIK antibodyAnti-NBK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance