Anti-BHMT antibody [8C11H5] (STJ97863)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant fragment of BHMT expressed in E. Coli.
General Information
| Short Description | Mouse monoclonal anti-Betaine--homocysteine S-methyltransferase 1 for use in WB, IHC, IF and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 8C11H5 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000IHC 1:200-1:1000ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BHMT |
| Gene ID | 635 |
| Uniprot ID | BHMT1_HUMAN |
| Immunogen | Purified recombinant fragment of BHMT expressed in E. Coli. |
| Specificity | BHMT Monoclonal Antibody detects endogenous levels of BHMT protein. |
Additional Info
| Function | Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. |
| Protein Name | Betaine--Homocysteine S-Methyltransferase 1 |
| Database Links | Reactome: R-HSA-1614635Reactome: R-HSA-6798163 |
| Cellular Localisation | CytoplasmCytosolNucleusPredominantly Localized In The Cytoplasm With A Small Fraction Detected In The NucleusTranslocates Into The Nucleus Upon Oxidative Stress |
| Alternative Antibody Names | Anti-Betaine--Homocysteine S-Methyltransferase 1 antibodyAnti-BHMT antibody |
Information sourced from Uniprot.org