Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Class A basic helix-loop-helix protein 15 is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
BHLHA15 |
Gene ID: |
168620 |
Uniprot ID: |
BHA15_HUMAN |
Specificity: |
This antibody detects endogenous levels of BHLHA15 at Human, Mouse, Rat |
Immunogen: |
Synthesized peptide derived from human BHLHA15 |
Function | Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'. |
Protein Name | Class A Basic Helix-Loop-Helix Protein 15Bhlha15Class B Basic Helix-Loop-Helix Protein 8Bhlhb8Muscle - Intestine And Stomach Expression 1Mist-1 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Class A Basic Helix-Loop-Helix Protein 15 antibodyAnti-Bhlha15 antibodyAnti-Class B Basic Helix-Loop-Helix Protein 8 antibodyAnti-Bhlhb8 antibodyAnti-Muscle - Intestine And Stomach Expression 1 antibodyAnti-Mist-1 antibodyAnti-BHLHA15 antibodyAnti-BHLHB8 antibodyAnti-MIST1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance