| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-BEX4 (N-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB. A dilution of 1:1000 is recommended. The optimal dilution should be determined by the end user. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
Bex4 |
| Gene ID: |
406217 |
| Uniprot ID: |
BEX4_MOUSE |
| Immunogen Region: |
N-Term |
| Specificity: |
Specific for BEX4. |
| Immunogen: |
A synthetic peptide from n-terminal region of mouse BEX4 conjugated to blue carrier protein was used as the antigen. |
| Post Translational Modifications | Ubiquitinated and degraded by the proteasome. |
| Function | May play a role in microtubule deacetylation by negatively regulating the SIRT2 deacetylase activity toward alpha-tubulin and thereby participate in the control of cell cycle progression and genomic stability. In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates. |
| Protein Name | Protein Bex4Brain-Expressed X-Linked Protein 4 |
| Cellular Localisation | CytoplasmCytoskeletonSpindle PoleNucleusAlso Localizes To Microtubules |
| Alternative Antibody Names | Anti-Protein Bex4 antibodyAnti-Brain-Expressed X-Linked Protein 4 antibodyAnti-Bex4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
