| Host: | Rabbit |
| Applications: | ELISA/IP/WB |
| Reactivity: | Bovine/Human/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-BEST3 (C-Term) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.5 µg/µl |
| Dilution Range: | WB: 1:500-1:1, 000DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:200ICC: 1:200IF: 1:200CFM: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | BEST3 |
| Gene ID: | 144453 |
| Uniprot ID: | BEST3_HUMAN |
| Immunogen Region: | C-Term |
| Immunogen: | Synthetic peptide taken within the last 50 amino acids from the C-terminus of human Bestrophin-3 protein. |
| Tissue Specificity | Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina. |
| Function | Ligand-gated anion channel that allows the movement of chloride monoatomic anions across cell membranes when activated by calcium (Ca2+). |
| Protein Name | Bestrophin-3Vitelliform Macular Dystrophy 2-Like Protein 3 |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Bestrophin-3 antibodyAnti-Vitelliform Macular Dystrophy 2-Like Protein 3 antibodyAnti-BEST3 antibodyAnti-VMD2L3 antibody |
Information sourced from Uniprot.org