| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Carotenoid-cleaving dioxygenase, mitochondrial for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BCO2 |
| Gene ID: | 83875 |
| Uniprot ID: | BCDO2_HUMAN |
| Specificity: | This antibody detects endogenous levels of BCO2 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human BCO2 |
| Function | Broad specificity mitochondrial dioxygenase that mediates the asymmetric oxidative cleavage of carotenoids. Cleaves carotenes (pure hydrocarbon carotenoids) such as all-trans-beta-carotene and lycopene as well as xanthophylls (oxygenated carotenoids) such as zeaxanthin, lutein and beta-cryptoxanthin at both the 9,10 and the 9',10' carbon-carbon double bond. Through its function in carotenoids metabolism regulates oxidative stress and the production of important signaling molecules. |
| Protein Name | Carotenoid-Cleaving Dioxygenase - MitochondrialB-Diox-IiBeta -Beta-Carotene 9' -10'-OxygenaseBeta-Carotene Dioxygenase 2 |
| Database Links | Reactome: R-HSA-975634 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Carotenoid-Cleaving Dioxygenase - Mitochondrial antibodyAnti-B-Diox-Ii antibodyAnti-Beta -Beta-Carotene 9' -10'-Oxygenase antibodyAnti-Beta-Carotene Dioxygenase 2 antibodyAnti-BCO2 antibodyAnti-BCDO2 antibody |
Information sourced from Uniprot.org
