Anti-BCL2L14/BCLG antibody (1-250) [S0MR] (STJ11103020)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal BCL2L14/BCLG (1-250) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S0MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BCL2L14 |
| Gene ID | 79370 |
| Uniprot ID | B2L14_HUMAN |
| Immunogen Region | 1-250 |
| Immunogen Sequence | MCSTSGCDLEEIPLDDDDLN TIEFKILAYYTRHHVFKSTP ALFSPKLLRTRSLSQRGLGN CSANESWTEVSWPCRNSQSS EKAINLGKKKSSWKAFFGVV EKEDSQSTPAKVSAQGQRTL EYQDSHSQQWSRCLSNVEQC LEHEAVDPKVISIANRVAEI VYSWPPPQATQAGGFKSKEI FVTEGLSFQLQGHVPVASSS KKDEEEQILAKIVELLKYSG DQLERKLKKDKALMGHFQD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human BCL2L14/BCLG (Q9BZR8). |
Additional Info
| Tissue Specificity | Isoform 1 is widely expressed. Isoform 2 is testis-specific. |
| Post Translational Modifications | Phosphorylated by MELK, leading to inhibit its pro-apoptotic function. |
| Function | Plays a role in apoptosis. |
| Protein Name | Apoptosis Facilitator Bcl-2-Like Protein 14Bcl2-L-14Apoptosis Regulator Bcl-G |
| Database Links | Reactome: R-HSA-6803205 |
| Cellular Localisation | CytoplasmIsoform 1: CytoplasmCytosolDiffusely Distributed Throughout The CytosolIsoform 2: Endomembrane SystemPredominantly Localized To Cytosolic Organelles |
| Alternative Antibody Names | Anti-Apoptosis Facilitator Bcl-2-Like Protein 14 antibodyAnti-Bcl2-L-14 antibodyAnti-Apoptosis Regulator Bcl-G antibodyAnti-BCL2L14 antibodyAnti-BCLG antibody |
Information sourced from Uniprot.org