| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:10-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BCL2L14 |
| Gene ID: | 79370 |
| Uniprot ID: | B2L14_HUMAN |
| Immunogen Region: | 1-327 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-327 of human BCL2L14/BCLG (NP_620049.1). |
| Immunogen Sequence: | MCSTSGCDLEEIPLDDDDLN TIEFKILAYYTRHHVFKSTP ALFSPKLLRTRSLSQRGLGN CSANESWTEVSWPCRNSQSS EKAINLGKKKSSWKAFFGVV EKEDSQSTPAKVSAQGQRTL EYQDSHSQQWSRCLSNVEQC LEHEAVDPKVISIANRVAEI VYSWPPPQATQAGGFKSKEI FVTEGLSFQLQGHVPVASSS KKDEEEQILAKIVELLKYSG DQLERKLKKDKALMGHFQD |
| Tissue Specificity | Isoform 1 is widely expressed. Isoform 2 is testis-specific. |
| Post Translational Modifications | Phosphorylated by MELK, leading to inhibit its pro-apoptotic function. |
| Function | Plays a role in apoptosis. |
| Protein Name | Apoptosis Facilitator Bcl-2-Like Protein 14Bcl2-L-14Apoptosis Regulator Bcl-G |
| Database Links | Reactome: R-HSA-6803205 |
| Cellular Localisation | CytoplasmIsoform 1: CytoplasmCytosolDiffusely Distributed Throughout The CytosolIsoform 2: Endomembrane SystemPredominantly Localized To Cytosolic Organelles |
| Alternative Antibody Names | Anti-Apoptosis Facilitator Bcl-2-Like Protein 14 antibodyAnti-Bcl2-L-14 antibodyAnti-Apoptosis Regulator Bcl-G antibodyAnti-BCL2L14 antibodyAnti-BCLG antibody |
Information sourced from Uniprot.org