Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-bcl-2 Oncoprotein is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | BCL-2/100/D5 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Tissue culture supernatant with sodium azide |
Concentration: | >=56 mg/L |
Dilution Range: | IHC-P 1:100 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Immunogen: | Synthetic peptide sequence (GAAPAPGIFSSQPGC-COOH). |
Background | Bcl-2 is a member of a family of proteins that are involved in apoptosis. Bcl-2 is an integral inner mitochondrial membrane protein of 25 kD and has a wide tissue distribution. It is considered to act as an inhibitor of apoptosis. For this reason, bcl-2 expression is inhibited in germinal centers where apoptosis forms part of the B cell production pathway. |
Information sourced from Uniprot.org