• Western blot analysis of extracts of various cell lines, using BANP antibody (STJ29732) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-BANP antibody (1-260) (STJ29732)

SKU:
STJ29732

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BANP (1-260) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BANP
Gene ID: 54971
Uniprot ID: BANP_HUMAN
Immunogen Region: 1-260
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human BANP (NP_060339.2).
Immunogen Sequence: MMSEHDLADVVQIAVEDLSP DHPVVLENHVVTDEDEPALK RQRLEINCQDPSIKSFLYSI NQTICLRLDSIEAKLQALEA TCKSLEEKLDLVTNKQHSPI QVPMVAGSPLGATQTCNKVR CAVPGRRQNTIVVKVPGQED SHHEDGESGSEASDSVSSCG QAGSQSIGSNVTLITLNSEE DYPNGTWLGDENNPEMRVRC AIIPSDMLHISTNCRTAEKM ALTLLDYLFHREVQAVSNL
Tissue Specificity Down-regulated in breast cancer cell lines.
Function Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell cycle arrest.
Protein Name Protein Banp
Ben Domain-Containing Protein 1
Btg3-Associated Nuclear Protein
Scaffold/Matrix-Associated Region-1-Binding Protein
Database Links Reactome: R-HSA-6804759
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Protein Banp antibody
Anti-Ben Domain-Containing Protein 1 antibody
Anti-Btg3-Associated Nuclear Protein antibody
Anti-Scaffold/Matrix-Associated Region-1-Binding Protein antibody
Anti-BANP antibody
Anti-BEND1 antibody
Anti-SMAR1 antibody

Information sourced from Uniprot.org

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