| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-BAMBI (21-152) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BAMBI |
| Gene ID: |
25805 |
| Uniprot ID: |
BAMBI_HUMAN |
| Immunogen Region: |
21-152 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 21-152 of human BAMBI (NP_036474.1). |
| Immunogen Sequence: |
VLLTKGEIRCYCDAAHCVAT GYMCKSELSACFSRLLDPQN SNSPLTHGCLDSLASTTDIC QAKQARNHSGTTIPTLECCH EDMCNYRGLHDVLSPPRGEA SGQGNRYQHDGSRNLITKVQ ELTSSKELWFRA |
| Tissue Specificity | High expression in kidney medulla, placenta and spleen.low in kidney cortex, liver, prostate and gut. Not expressed in normal skin, expression is high in melanocytes and in 3 out of 11 melanoma metastases tested. |
| Function | Negatively regulates TGF-beta signaling. |
| Protein Name | Bmp And Activin Membrane-Bound Inhibitor HomologNon-Metastatic Gene A ProteinPutative Transmembrane Protein Nma |
| Database Links | Reactome: R-HSA-2173788 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Bmp And Activin Membrane-Bound Inhibitor Homolog antibodyAnti-Non-Metastatic Gene A Protein antibodyAnti-Putative Transmembrane Protein Nma antibodyAnti-BAMBI antibodyAnti-NMA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
