| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BAMBI |
| Gene ID: | 25805 |
| Uniprot ID: | BAMBI_HUMAN |
| Immunogen Region: | 21-152 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-152 of human BAMBI (NP_036474.1). |
| Immunogen Sequence: | VLLTKGEIRCYCDAAHCVAT GYMCKSELSACFSRLLDPQN SNSPLTHGCLDSLASTTDIC QAKQARNHSGTTIPTLECCH EDMCNYRGLHDVLSPPRGEA SGQGNRYQHDGSRNLITKVQ ELTSSKELWFRA |
| Tissue Specificity | High expression in kidney medulla, placenta and spleen.low in kidney cortex, liver, prostate and gut. Not expressed in normal skin, expression is high in melanocytes and in 3 out of 11 melanoma metastases tested. |
| Function | Negatively regulates TGF-beta signaling. |
| Protein Name | Bmp And Activin Membrane-Bound Inhibitor HomologNon-Metastatic Gene A ProteinPutative Transmembrane Protein Nma |
| Database Links | Reactome: R-HSA-2173788 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Bmp And Activin Membrane-Bound Inhibitor Homolog antibodyAnti-Non-Metastatic Gene A Protein antibodyAnti-Putative Transmembrane Protein Nma antibodyAnti-BAMBI antibodyAnti-NMA antibody |
Information sourced from Uniprot.org