Anti-Bak antibody [SRM13019] (STJ11107749)

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STJ11107749
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM13019
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB, 1:100-1:500
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BAK1
Gene ID: 578
Uniprot ID: BAK_HUMAN
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Immunogen Sequence: Human
Function Plays a role in the mitochondrial apoptotic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases.
Protein Name Bcl-2 Homologous Antagonist/Killer
Apoptosis Regulator Bak
Bcl-2-Like Protein 7
Bcl2-L-7
Database Links Reactome: R-HSA-111452
Reactome: R-HSA-111457
Reactome: R-HSA-5620971
Cellular Localisation Mitochondrion Outer Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Bcl-2 Homologous Antagonist/Killer antibody
Anti-Apoptosis Regulator Bak antibody
Anti-Bcl-2-Like Protein 7 antibody
Anti-Bcl2-L-7 antibody
Anti-BAK1 antibody
Anti-BAK antibody
Anti-BCL2L7 antibody
Anti-CDN1 antibody

Information sourced from Uniprot.org

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