Function | Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network. By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones. May regulate behavior and food intake by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin. Proposed to play a role in hypothalamic neuronal firing by modulating gamma-aminobutyric acid (GABA)ergic inhibitory neurotransmission. |
Protein Name | Bai1-Associated Protein 3Bap3Brain-Specific Angiogenesis Inhibitor I-Associated Protein 3 |
Cellular Localisation | CytoplasmCytosolRecycling Endosome MembranePeripheral Membrane ProteinLate Endosome MembraneGolgi ApparatusTrans-Golgi Network MembraneCell MembraneRapidly Recruited To The Plasma Membrane And To Golgi Structures In Response To Increased Intracellular Calcium Concentration |
Alternative Antibody Names | Anti-Bai1-Associated Protein 3 antibodyAnti-Bap3 antibodyAnti-Brain-Specific Angiogenesis Inhibitor I-Associated Protein 3 antibodyAnti-BAIAP3 antibodyAnti-KIAA0734 antibody |
Information sourced from Uniprot.org