| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-BAI1-associated protein 3 (248-298 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BAIAP3 |
| Gene ID: |
8938 |
| Uniprot ID: |
BAIP3_HUMAN |
| Immunogen Region: |
248-298 aa |
| Specificity: |
This antibody detects endogenous levels of BAIP3 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human BAIP3 at the amino acid range 248-298 |
| Function | Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network. By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones. May regulate behavior and food intake by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin. Proposed to play a role in hypothalamic neuronal firing by modulating gamma-aminobutyric acid (GABA)ergic inhibitory neurotransmission. |
| Protein Name | Bai1-Associated Protein 3Bap3Brain-Specific Angiogenesis Inhibitor I-Associated Protein 3 |
| Cellular Localisation | CytoplasmCytosolRecycling Endosome MembranePeripheral Membrane ProteinLate Endosome MembraneGolgi ApparatusTrans-Golgi Network MembraneCell MembraneRapidly Recruited To The Plasma Membrane And To Golgi Structures In Response To Increased Intracellular Calcium Concentration |
| Alternative Antibody Names | Anti-Bai1-Associated Protein 3 antibodyAnti-Bap3 antibodyAnti-Brain-Specific Angiogenesis Inhibitor I-Associated Protein 3 antibodyAnti-BAIAP3 antibodyAnti-KIAA0734 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
