| Host: | Rabbit |
| Applications: | IF/ICC/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BAIAP2L1 |
| Gene ID: | 55971 |
| Uniprot ID: | BI2L1_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human BAIAP2L1 (NP_061330.2). |
| Immunogen Sequence: | MSRGPEEVNRLTESTYRNVM EQFNPGLRNLINLGKNYEKA VNAMILAGKAYYDGVAKIGE IATGSPVSTELGHVLIEISS THKKLNESLDENFKKFHKEI IHELEKKIELDVKYMNATLK RYQTEHKNKLESLEKSQAEL KKIRRKSQGSRNALKYEHKE IEYVETVTSRQSEIQKFIAD GCKEALLEEKRRFCFLVDKH CGFANHIHYYHLQSAELLNS KLPRWQETCVDAIKVPEKI |
| Post Translational Modifications | Phosphorylated on tyrosine in response to insulin. |
| Function | May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. |
| Protein Name | Bar/Imd Domain-Containing Adapter Protein 2-Like 1Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2-Like Protein 1Bai1-Associated Protein 2-Like Protein 1Insulin Receptor Tyrosine Kinase Substrate |
| Database Links | Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013423Reactome: R-HSA-9035034 |
| Cellular Localisation | CytoplasmCytoskeletonRecruited To Actin Pedestals That Are Formed Upon Infection By Bacteria At Bacterial Attachment Sites |
| Alternative Antibody Names | Anti-Bar/Imd Domain-Containing Adapter Protein 2-Like 1 antibodyAnti-Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2-Like Protein 1 antibodyAnti-Bai1-Associated Protein 2-Like Protein 1 antibodyAnti-Insulin Receptor Tyrosine Kinase Substrate antibodyAnti-BAIAP2L1 antibodyAnti-IRTKS antibody |
Information sourced from Uniprot.org