| Host: |
Goat |
| Applications: |
Pep-ELISA/WB-Trf/IHC |
| Reactivity: |
Human/Dog/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-BAIAP2-isoform 3 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
IHC-3.75µg/mlELISA-antibody detection limit dilution 1:8000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
BAIAP2 |
| Gene ID: |
10458 |
| Uniprot ID: |
BAIP2_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_006331.1 |
| Specificity: |
This antibody will recognise only one of three reported isoforms (NP_006331.1). |
| Immunogen Sequence: |
SMSSADVEVARF |
| Post Translational Modifications | Phosphorylated on tyrosine residues by INSR in response to insulin treatment. |
| Function | Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions. |
| Protein Name | Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2Bai-Associated Protein 2Bai1-Associated Protein 2Protein Bap2Fas Ligand-Associated Factor 3Flaf3Insulin Receptor Substrate P53/P58Irs-58Irsp53/58Insulin Receptor Substrate Protein Of 53 KdaIrsp53Insulin Receptor Substrate P53 |
| Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-4420097Reactome: R-HSA-5663213Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013423Reactome: R-HSA-9664422 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinCell ProjectionFilopodiumRuffleCytoskeletonDetected Throughout The Cytoplasm In The Absence Of Specific Binding PartnersDetected In Filopodia And Close To Membrane RufflesRecruited To Actin Pedestals That Are Formed Upon Infection By Bacteria At Bacterial Attachment Sites |
| Alternative Antibody Names | Anti-Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 antibodyAnti-Bai-Associated Protein 2 antibodyAnti-Bai1-Associated Protein 2 antibodyAnti-Protein Bap2 antibodyAnti-Fas Ligand-Associated Factor 3 antibodyAnti-Flaf3 antibodyAnti-Insulin Receptor Substrate P53/P58 antibodyAnti-Irs-58 antibodyAnti-Irsp53/58 antibodyAnti-Insulin Receptor Substrate Protein Of 53 Kda antibodyAnti-Irsp53 antibodyAnti-Insulin Receptor Substrate P53 antibodyAnti-BAIAP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
