| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-BAG family molecular chaperone regulator 4 (C-Term) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BAG4 |
| Gene ID: | 9530 |
| Uniprot ID: | BAG4_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | Bag-4 Polyclonal Antibody detects endogenous levels of Bag-4 protein. |
| Immunogen: | Synthesized peptide derived from the C-terminal region of human Bag-4. |
| Function | Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Prevents constitutive TNFRSF1A signaling. Negative regulator of PRKN translocation to damaged mitochondria. |
| Protein Name | Bag Family Molecular Chaperone Regulator 4Bag-4Bcl-2-Associated Athanogene 4Silencer Of Death Domains |
| Database Links | Reactome: R-HSA-3371453Reactome: R-HSA-5655302Reactome: R-HSA-75893Reactome: R-HSA-8853336 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Bag Family Molecular Chaperone Regulator 4 antibodyAnti-Bag-4 antibodyAnti-Bcl-2-Associated Athanogene 4 antibodyAnti-Silencer Of Death Domains antibodyAnti-BAG4 antibodyAnti-SODD antibody |
Information sourced from Uniprot.org
