Host: |
Rabbit |
Applications: |
WB/IP |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-BACH1 (1-736) is suitable for use in Western Blot and Immunoprecipitation research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:1000-1:5000IP 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
BACH1 |
Gene ID: |
571 |
Uniprot ID: |
BACH1_HUMAN |
Immunogen Region: |
1-736 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-736 of human BACH1 (NP_996749.1). |
Immunogen Sequence: |
MSLSENSVFAYESSVHSTNV LLSLNDQRKKDVLCDVTIFV EGQRFRAHRSVLAACSSYFH SRIVGQADGELNITLPEEVT VKGFEPLIQFAYTAKLILSK ENVDEVCKCVEFLSVHNIEE SCFQFLKFKFLDSTADQQEC PRKKCFSSHCQKTDLKLSLL DQRDLETDEVEEFLENKNVQ TPQCKLRRYQGNAKASPPLQ DSASQTYESMCLEKDAALAL PSLCPKYRKFQKAFGTDRV |
Post Translational Modifications | Ubiquitinated by the SCF(FBXL17) complex, leading to its degradation by the proteasome. |
Function | Transcriptional regulator that acts as repressor or activator, depending on the context. Binds to NF-E2 DNA binding sites. Plays important roles in coordinating transcription activation and repression by MAFK. Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway. |
Protein Name | Transcription Regulator Protein Bach1Btb And Cnc Homolog 1Ha2303 |
Database Links | Reactome: R-HSA-9707587Reactome: R-HSA-9707616Reactome: R-HSA-9708530Reactome: R-HSA-9818027 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Transcription Regulator Protein Bach1 antibodyAnti-Btb And Cnc Homolog 1 antibodyAnti-Ha2303 antibodyAnti-BACH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance