Anti-B3GAT1 antibody [IHC539] (STJA0041993)

SKU:
STJA0041993
£115.50 - £261.50
Processing The item has been added

Host: Mouse
Applications: IHC-p
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-B3GAT1 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : IHC539
Conjugation: Unconjugated
Isotype: IgM
Formulation: Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Dilution Range: 1:100-1:200
Storage Instruction: Store at 2-8°C for up to 1 year. Do not freeze.
Gene Symbol: B3GAT1
Gene ID: 27087
Uniprot ID: B3GA1_HUMAN
Specificity: Tested and validated on tonsil tissue.
Immunogen: Human CD57 protein.
Tissue Specificity Mainly expressed in the brain.
Post Translational Modifications The soluble form derives from the membrane form by proteolytic processing.
Function Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
Protein Name Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1
Beta-1 -3-Glucuronyltransferase 1
Glucuronosyltransferase P
Glcat-P
Udp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase
Glcuat-P
Database Links Reactome: R-HSA-1971475
Cellular Localisation Isoform 1: Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Isoform 2: Golgi Apparatus Membrane
Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 antibody
Anti-Beta-1 -3-Glucuronyltransferase 1 antibody
Anti-Glucuronosyltransferase P antibody
Anti-Glcat-P antibody
Anti-Udp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase antibody
Anti-Glcuat-P antibody
Anti-B3GAT1 antibody
Anti-GLCATP antibody

Information sourced from Uniprot.org