Anti-AZI2 antibody (10-59) (STJ94343)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human AZI2. AA range:10-59
General Information
| Short Description | Rabbit polyclonal anti-5-azacytidine-induced protein 2 (10-59) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AZI2 |
| Gene ID | 64343 |
| Uniprot ID | AZI2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AZI2. AA range:10-59 |
| Immunogen Region | 10-59 |
| Specificity | Nap1 Polyclonal Antibody detects endogenous levels of Nap1 protein. |
Additional Info
| Tissue Specificity | Widely expressed. Abundant expression seen in the pancreas and testis. |
| Post Translational Modifications | Ubiquitinated via 'Lys-48'-linked polyubiquitination by TRIM38, leading to its degradation. |
| Function | Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1. |
| Protein Name | 5-Azacytidine-Induced Protein 2Nf-Kappa-B-Activating Kinase-Associated Protein 1Nak-Associated Protein 1Nap1Tilp |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-5-Azacytidine-Induced Protein 2 antibodyAnti-Nf-Kappa-B-Activating Kinase-Associated Protein 1 antibodyAnti-Nak-Associated Protein 1 antibodyAnti-Nap1 antibodyAnti-Tilp antibodyAnti-AZI2 antibodyAnti-NAP1 antibodyAnti-TBKBP2 antibody |
Information sourced from Uniprot.org