| Function | Acyltransferase that catalyzes the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters. Shows a preference for medium chain acyl-CoAs from C12 to C16 in length and fatty alcohols shorter than C20, as the acyl donors and acceptors, respectively. Also possesses acyl-CoA retinol acyltransferase (ARAT) activity that preferentially esterifies 11-cis-retinol, a chromophore precursor of bleached opsin pigments in cone cells. Shows higher catalytic efficiency toward 11-cis-retinol versus 9-cis-retinol, 13-cis-retinol, and all-trans-retinol substrates. |
| Protein Name | Acyl-Coa Wax Alcohol Acyltransferase 211-Cis-Specific Retinyl-Ester Synthase11-Cis-Re-SynthaseAcyl-Coa Retinol O-Fatty-AcyltransferaseAratRetinol O-Fatty-AcyltransferaseDiacylglycerol O-Acyltransferase 2-Like Protein 4Diacylglycerol O-Acyltransferase Candidate 4Hdc4Long-Chain-Alcohol O-Fatty-Acyltransferase 2Multifunctional O-AcyltransferaseWax SynthaseHws |
| Database Links | Reactome: R-HSA-1482883Reactome: R-HSA-2187335Reactome: R-HSA-9640463 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Acyl-Coa Wax Alcohol Acyltransferase 2 antibodyAnti-11-Cis-Specific Retinyl-Ester Synthase antibodyAnti-11-Cis-Re-Synthase antibodyAnti-Acyl-Coa Retinol O-Fatty-Acyltransferase antibodyAnti-Arat antibodyAnti-Retinol O-Fatty-Acyltransferase antibodyAnti-Diacylglycerol O-Acyltransferase 2-Like Protein 4 antibodyAnti-Diacylglycerol O-Acyltransferase Candidate 4 antibodyAnti-Hdc4 antibodyAnti-Long-Chain-Alcohol O-Fatty-Acyltransferase 2 antibodyAnti-Multifunctional O-Acyltransferase antibodyAnti-Wax Synthase antibodyAnti-Hws antibodyAnti-AWAT2 antibodyAnti-DC4 antibodyAnti-DGAT2L4 antibodyAnti-MFAT antibodyAnti-WS antibody |
Information sourced from Uniprot.org
