| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:3000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AVEN |
| Gene ID: | 57099 |
| Uniprot ID: | AVEN_HUMAN |
| Immunogen Region: | 203-362 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 203-362 of human AVEN (NP_065104.1). |
| Immunogen Sequence: | VQGTVPLEVPQVKPKRTDDG KGLGMQLKGPLGPGGRGPIF ELKSVAAGCPVLLGKDNPSP GPSRDSQKPTSPLQSAGDHL EEELDLLLNLDAPIKEGDNI LPDQTSQDLKSKEDGEVVQE EEVCAKPSVTEEKNMEPEQP STSKNVTEEELEDWLDSMIS |
| Tissue Specificity | Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas. |
| Function | Protects against apoptosis mediated by Apaf-1. |
| Protein Name | Cell Death Regulator Aven |
| Database Links | Reactome: R-HSA-111458Reactome: R-HSA-9627069 |
| Cellular Localisation | Endomembrane SystemPeripheral Membrane ProteinAssociated With Intracellular Membranes |
| Alternative Antibody Names | Anti-Cell Death Regulator Aven antibodyAnti-AVEN antibody |
Information sourced from Uniprot.org