Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-All-trans retinoic acid-induced differentiation factor (1-80 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ATRAID |
Gene ID: |
51374 |
Uniprot ID: |
ARAID_HUMAN |
Immunogen Region: |
1-80 aa |
Specificity: |
ARAID Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 1-80 |
Function | Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway. In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containing-bisphophonates (N-BPs) required for releasing N-BP molecules that have trafficked to lysosomes through fluid-phase endocytosis into the cytosol. |
Protein Name | All-Trans Retinoic Acid-Induced Differentiation FactorApoptosis-Related Protein 3Apr-3P18 |
Cellular Localisation | Nucleus EnvelopeCell MembraneSingle-Pass Membrane ProteinLysosome MembraneMulti-Pass Membrane ProteinColocalizes With Nell1 On The Nuclear Envelope And The Perinuclear Region |
Alternative Antibody Names | Anti-All-Trans Retinoic Acid-Induced Differentiation Factor antibodyAnti-Apoptosis-Related Protein 3 antibodyAnti-Apr-3 antibodyAnti-P18 antibodyAnti-ATRAID antibodyAnti-APR3 antibodyAnti-C2orf28 antibodyAnti-HSPC013 antibodyAnti-UNQ214 antibodyAnti-PRO240 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance