| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-V-type proton ATPase subunit E 1 (156-206 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATP6V1E1 |
| Gene ID: | 529 |
| Uniprot ID: | VATE1_HUMAN |
| Immunogen Region: | 156-206 aa |
| Specificity: | This antibody detects endogenous levels of VATE1 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human VATE1 at the amino acid range 156-206 |
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. |
| Protein Name | V-Type Proton Atpase Subunit E 1 V-Atpase Subunit E 1 V-Atpase 31 Kda Subunit P31 Vacuolar Proton Pump Subunit E 1 |
| Database Links | Reactome: R-HSA-1222556 Reactome: R-HSA-77387 Reactome: R-HSA-917977 Reactome: R-HSA-9639288 Reactome: R-HSA-983712 Reactome: R-HSA-9857377 |
| Cellular Localisation | Apical Cell Membrane Peripheral Membrane Protein Cytoplasmic Vesicle Secretory Vesicle Synaptic Vesicle Membrane Clathrin-Coated Vesicle Membrane |
| Alternative Antibody Names | Anti-V-Type Proton Atpase Subunit E 1 antibody Anti-V-Atpase Subunit E 1 antibody Anti-V-Atpase 31 Kda Subunit antibody Anti-P31 antibody Anti-Vacuolar Proton Pump Subunit E 1 antibody Anti-ATP6V1E1 antibody Anti-ATP6E antibody Anti-ATP6E2 antibody |
Information sourced from Uniprot.org