Anti-ATP6V1C2 antibody (121-170 aa) (STJ96224)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ATP6V1C2 at the amino acid range 121-170
General Information
| Short Description | Rabbit polyclonal anti-V-type proton ATPase subunit C 2 (121-170 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATP6V1C2 |
| Gene ID | 245973 |
| Uniprot ID | VATC2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ATP6V1C2 at the amino acid range 121-170 |
| Immunogen Region | 121-170 aa |
| Specificity | V-ATPase C2 Polyclonal Antibody detects endogenous levels of V-ATPase C2 protein. |
Additional Info
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. |
| Protein Name | V-Type Proton Atpase Subunit C 2V-Atpase Subunit C 2Vacuolar Proton Pump Subunit C 2 |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-V-Type Proton Atpase Subunit C 2 antibodyAnti-V-Atpase Subunit C 2 antibodyAnti-Vacuolar Proton Pump Subunit C 2 antibodyAnti-ATP6V1C2 antibody |
Information sourced from Uniprot.org