| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
ATP6V1C2 |
| Gene ID: |
245973 |
| Uniprot ID: |
VATC2_HUMAN |
| Immunogen Region: |
1-280 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ATP6V1C2 (NP_653184.2). |
| Immunogen Sequence: |
MSEFWLISAPGDKENLQALE RMNTVTSKSNLSYNTKFAIP DFKVGTLDSLVGLSDELGKL DTFAESLIRRMAQSVVEVME DSKGKVQEHLLANGVDLTSF VTHFEWDMAKYPVKQPLVSV VDTIAKQLAQIEMDLKSRTA AYNTLKTNLENLEKKSMGNL FTRTLSDIVSKEDFVLDSEY LVTLLVIVPKPNYSQWQKTY ESLSDMVVPRSTKLITEDKE GGLFTVTLFRKVIEDFKTK |
| Tissue Specificity | Kidney and placenta. |
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. |
| Protein Name | V-Type Proton Atpase Subunit C 2V-Atpase Subunit C 2Vacuolar Proton Pump Subunit C 2 |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712 |
| Alternative Antibody Names | Anti-V-Type Proton Atpase Subunit C 2 antibodyAnti-V-Atpase Subunit C 2 antibodyAnti-Vacuolar Proton Pump Subunit C 2 antibodyAnti-ATP6V1C2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
