• Western blot analysis of ATP6V1B1 Antibody. The lane on the right is blocked with the ATP6V1B1 peptide.
  • Immunohistochemistryt analysis of paraffin-embedded human breast carcinoma, using ATP6V1B1 Antibody. The lane on the right is blocked with the ATP6V1B1 peptide.
  • Western blot analysis of various cells using V-ATPase B1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Anti-ATP6V1B1 antibody (381-430 aa) (STJ96223)

SKU:
STJ96223

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-V-type proton ATPase subunit B, kidney isoform (381-430 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ATP6V1B1
Gene ID: 525
Uniprot ID: VATB1_HUMAN
Immunogen Region: 381-430 aa
Specificity: V-ATPase B1 Polyclonal Antibody detects endogenous levels of V-ATPase B1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ATP6V1B1 at the amino acid range 381-430
Function Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Essential for the proper assembly and activity of V-ATPase. In renal intercalated cells, mediates secretion of protons (H+) into the urine thereby ensuring correct urinary acidification. Required for optimal olfactory function by mediating the acidification of the nasal olfactory epithelium.
Protein Name V-Type Proton Atpase Subunit B - Kidney Isoform
V-Atpase Subunit B 1
Endomembrane Proton Pump 58 Kda Subunit
Vacuolar Proton Pump Subunit B 1
Database Links Reactome: R-HSA-1222556
Reactome: R-HSA-77387
Reactome: R-HSA-917977
Reactome: R-HSA-9639288
Reactome: R-HSA-983712
Cellular Localisation Apical Cell Membrane
Basolateral Cell Membrane
Alternative Antibody Names Anti-V-Type Proton Atpase Subunit B - Kidney Isoform antibody
Anti-V-Atpase Subunit B 1 antibody
Anti-Endomembrane Proton Pump 58 Kda Subunit antibody
Anti-Vacuolar Proton Pump Subunit B 1 antibody
Anti-ATP6V1B1 antibody
Anti-ATP6B1 antibody
Anti-VATB antibody
Anti-VPP3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance