Anti-ATP6V0C antibody (37-50) (STJ118778)

Name: Anti-ATP6V0C antibody (37-50) (STJ118778)
SKU: STJ118778
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ118778

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Short Description	Rabbit polyclonal ATP6V0C (37-50) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	ATP6V0C
Gene ID	527
Uniprot ID	VATL_HUMAN
Immunogen Region	37-50
Immunogen Sequence	MSESKSGPEYASFFAVMGAS AAMVFSALGAAYGTAKSGTG IAAMSVMRPEQIMKSIIPVV MAGIIAIYGLVVAVLIANSL NDDISLYKSFLQLGAGLSVG
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ATP6V0C (NP_001185498.1).

Post Translational Modifications	Ubiquitinated by RNF182, leading to its degradation via the ubiquitin-proteasome pathway.
Function	Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments, and in some cell types, it is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
Protein Name	V-Type Proton Atpase 16 Kda Proteolipid Subunit C V-Atpase 16 Kda Proteolipid Subunit C Vacuolar Proton Pump 16 Kda Proteolipid Subunit C
Database Links	Reactome: R-HSA-1222556 Reactome: R-HSA-6798695 Reactome: R-HSA-77387 Reactome: R-HSA-917977 Reactome: R-HSA-9639288 Reactome: R-HSA-983712 Reactome: R-HSA-9857377
Cellular Localisation	Cytoplasmic Vesicle Clathrin-Coated Vesicle Membrane Multi-Pass Membrane Protein Secretory Vesicle Synaptic Vesicle Membrane
Alternative Antibody Names	Anti-V-Type Proton Atpase 16 Kda Proteolipid Subunit C antibody Anti-V-Atpase 16 Kda Proteolipid Subunit C antibody Anti-Vacuolar Proton Pump 16 Kda Proteolipid Subunit C antibody Anti-ATP6V0C antibody Anti-ATP6C antibody Anti-ATP6L antibody Anti-ATPL antibody

Information sourced from Uniprot.org