| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ATP6V0C (37-50) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ATP6V0C |
| Gene ID: |
527 |
| Uniprot ID: |
VATL_HUMAN |
| Immunogen Region: |
37-50 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 37-50 of human ATP6V0C (NP_001185498.1). |
| Immunogen Sequence: |
SGTGIAAMSVMRPE |
| Post Translational Modifications | Ubiquitinated by RNF182, leading to its degradation via the ubiquitin-proteasome pathway. |
| Function | Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. |
| Protein Name | V-Type Proton Atpase 16 Kda Proteolipid Subunit CV-Atpase 16 Kda Proteolipid Subunit CVacuolar Proton Pump 16 Kda Proteolipid Subunit C |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-6798695Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712 |
| Cellular Localisation | Cytoplasmic VesicleClathrin-Coated Vesicle MembraneMulti-Pass Membrane ProteinSecretory VesicleSynaptic Vesicle Membrane |
| Alternative Antibody Names | Anti-V-Type Proton Atpase 16 Kda Proteolipid Subunit C antibodyAnti-V-Atpase 16 Kda Proteolipid Subunit C antibodyAnti-Vacuolar Proton Pump 16 Kda Proteolipid Subunit C antibodyAnti-ATP6V0C antibodyAnti-ATP6C antibodyAnti-ATP6L antibodyAnti-ATPL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
