Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ATP synthase subunit gamma, mitochondrial (131-180 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ATP5F1C |
Gene ID: |
509 |
Uniprot ID: |
ATPG_HUMAN |
Immunogen Region: |
131-180 aa |
Specificity: |
ATP5C1 Polyclonal Antibody detects endogenous levels of ATP5C1 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human ATP5C1 at the amino acid range 131-180 |
Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. |
Protein Name | Atp Synthase Subunit Gamma - MitochondrialAtp Synthase F1 Subunit GammaF-Atpase Gamma Subunit |
Database Links | Reactome: R-HSA-163210Reactome: R-HSA-8949613 |
Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
Alternative Antibody Names | Anti-Atp Synthase Subunit Gamma - Mitochondrial antibodyAnti-Atp Synthase F1 Subunit Gamma antibodyAnti-F-Atpase Gamma Subunit antibodyAnti-ATP5F1C antibodyAnti-ATP5C antibodyAnti-ATP5C1 antibodyAnti-ATP5CL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance