| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Plasma membrane calcium-transporting ATPase 3 (140-220 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATP2B3 |
| Gene ID: | 492 |
| Uniprot ID: | AT2B3_HUMAN |
| Immunogen Region: | 140-220 aa |
| Specificity: | AT2B3 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 140-220 |
| Function | ATP-driven Ca(2+) ion pump involved in the maintenance of basal intracellular Ca(2+) levels at the presynaptic terminals. Uses ATP as an energy source to transport cytosolic Ca(2+) ions across the plasma membrane to the extracellular compartment. May counter-transport protons, but the mechanism and the stoichiometry of this Ca(2+)/H(+) exchange remains to be established. |
| Protein Name | Plasma Membrane Calcium-Transporting Atpase 3Pmca3Plasma Membrane Calcium Atpase Isoform 3Plasma Membrane Calcium Pump Isoform 3 |
| Database Links | Reactome: R-HSA-418359Reactome: R-HSA-5578775Reactome: R-HSA-936837 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPresynaptic Cell MembraneLocalized At Parallel Fiber Terminals |
| Alternative Antibody Names | Anti-Plasma Membrane Calcium-Transporting Atpase 3 antibodyAnti-Pmca3 antibodyAnti-Plasma Membrane Calcium Atpase Isoform 3 antibodyAnti-Plasma Membrane Calcium Pump Isoform 3 antibodyAnti-ATP2B3 antibody |
Information sourced from Uniprot.org