| Tissue Specificity | Specifically expressed in testis. Found in very low levels in skeletal muscle. Expressed in mature sperm (at protein level). |
| Function | This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Plays a role in sperm motility. |
| Protein Name | Sodium/Potassium-Transporting Atpase Subunit Alpha-4Na(+/K(+ Atpase Alpha-4 SubunitSodium Pump Subunit Alpha-4 |
| Database Links | Reactome: R-HSA-5578775Reactome: R-HSA-936837Reactome: R-HSA-9679191 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinIn Mature SpermLocated In The Principle Piece Of The Sperm Flagellum |
| Alternative Antibody Names | Anti-Sodium/Potassium-Transporting Atpase Subunit Alpha-4 antibodyAnti-Na(+/K(+ Atpase Alpha-4 Subunit antibodyAnti-Sodium Pump Subunit Alpha-4 antibodyAnti-ATP1A4 antibodyAnti-ATP1AL2 antibody |
Information sourced from Uniprot.org
